Synthesis and Antioxidant Properties of Novel Quinazoline Derivatives

Authors

  • Zenta Tetere Riga Technical University
  • Daina Zicāne Riga Technical University
  • Irisa Rāviņa Riga Technical University
  • Inese Mieriņa Riga Technical University
  • Inese Rijkure Riga Technical University

DOI:

https://doi.org/10.7250/msac.2014.009

Abstract

Quinazoline derivatives have expressed a broad spectrum of biological activities, but there are few examples in literature on an antioxidant activity of different quinazolines. On the basis of literature by Chinese scientists on the effective antioxidant activity of Schiff bases containing 2-oxoquinoline and due to structural similarity of quinoline and quinazoline ring systems, the reactions of 3-aminoquinazolinone with a range of aromatic aldehydes and ethoxymethylene derivatives have been carried out and their radical scavenging activities have been studied.

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Published

05.09.2014